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Rev. méd. Maule ; 34(2): 30-40, dic. 2019. tab
Article in Spanish | LILACS | ID: biblio-1371248

ABSTRACT

Myasthenia gravis is an acquired autoimmune disorder of the neuromuscular junction characterized by fluctuating weakness and fatigability of skeletal muscles. The diagnosis can be established by clinical and serologic testing, with predominance of autoantibodies against the acetylcholine receptor, and Muscle-specific kinase antibodies. We report two cases of Myasthenia gravis, the first one is a 31 year old patient with a debut of the disease, mainly with bulbar symptoms, and the second one is a 29 year old patient diagnosed with generalized Miasthenia Gravis also mainly with bulbar symptoms with worsening of symptomatology. In this report treatments alternatives and management approaches are discused


Subject(s)
Humans , Female , Adult , Myasthenia Gravis/immunology , Myasthenia Gravis/drug therapy , Pyridostigmine Bromide/therapeutic use , Thymectomy , Immunoglobulins, Intravenous/therapeutic use , Glucocorticoids/therapeutic use , Immunosuppressive Agents/therapeutic use , Immunotherapy , Myasthenia Gravis/surgery , Myasthenia Gravis/classification
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